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藥物納米晶體輸送系統(tǒng)

“通過高壓臥式珠(球)磨機生產(chǎn)的藥物納米晶體。高壓臥式珠(球)磨機已經(jīng)應用在生產(chǎn)乳液和懸浮液的各個領(lǐng)域中多年,并且目前用于食品工業(yè),例如牛奶的均質(zhì)化。該技術(shù)的一個明顯優(yōu)勢是易于擴展,甚至可以擴展到非常大的容量。在制藥工業(yè)中,通過該技術(shù)生產(chǎn)腸胃外乳液。”

Dispermat SL示意圖

圖:采用再循環(huán)方法的珠(球)磨機Dispermat SL示意圖


文獻原文

NANOPARTICULATE DRUG DELIVERY SYSTEMS

“Drug Nanocrystals produced by High- Pressure Homogenization. High-pressure homogenization has been applied for many years in various areas for the production of emulsions and suspensions and is currently used in food industry like homogenization of milk. A distinct advantage of this technology is its ease for scaling up, even to very large volumes. In the pharmaceutical industry parenteral emulsions are produced by this technology.”

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